I have been playing this for the last couple of weeks - I think I have done most of the side-quests and about 90% of the main campaign. I recorded a little video of 'VAULT 22', one of the interesting little side-quests that sends you into a Vault filled with plants.

http://www.sectorgame.com/upload/FalloutNV24.mp4

Right click - Save as to watch

Oh yeah, I played this

Didn't finish the main quest though because I always get killed...

I haven't finished the final quests yet - I don't intend to until I have found every last side-quest and completed all the upcoming DLCs.